Canine distemper is a highly contagious infectious disease caused by the canine distemper virus, primarily transmitted through saliva and air. Once infected, the condition is often critical, and dogs that have not been vaccinated are most susceptible.
Symptoms of Canine Distemper
Early Infection Symptoms
The symptoms in the early stage of infection are similar to those of a common cold, usually improving after a few days. However, three to five days later, the dog may experience a fever again, with a body temperature reaching around 41°C, and the condition will worsen. Therefore, canine distemper is also known as biphasic fever.
Mid-Infection Symptoms
During the mid-stage of infection, dogs may exhibit white nasal discharge and mild coughing, but they can still eat and drink daily. The symptoms may seem severe yet not severe. However, do not be deceived by this appearance, as the mortality rate of canine distemper exceeds 60%.
Late Infection Symptoms
In the late stage of infection, the symptoms resemble pneumonia, mainly characterized by coughing, rapid breathing, thick yellow nasal discharge, and purulent eye discharge, which may cause nasal blockage. For dogs, significant weight loss and extreme emaciation occur. The mortality rate of the disease exceeds 80%, but it is not immediately fatal in a short period.
Terminal Infection Symptoms
In the terminal stage of infection, neurological symptoms appear, such as generalized convulsions, hemiplegia, teeth chattering, drooling, and diarrhea with blood. At this point, the dog is essentially beyond saving, but the process may last three to five days before it passes away. Therefore, both the dog and the owner endure great suffering during this period. I personally suggest considering euthanasia.

How to Diagnose Canine Distemper
If your dog exhibits the aforementioned symptoms, it is crucial to take it seriously. First, we can use a canine distemper test card to detect whether the dog is infected. If the test card shows two lines, it is almost certain that the dog is infected with canine distemper. Therefore, be mentally prepared. If you have other dogs at home, isolate the sick dog immediately to a place where other dogs cannot reach it, and disinfect the items that have been in contact with the sick dog using a dedicated disinfectant to prevent the virus from spreading to other dogs.
Medication Treatment
Symptomatic Treatment
In terms of medication, we first adopt symptomatic treatment.
- The dosage of Ceftriaxone is 0.1 mg per kilogram of body weight;
- The dosage of Karamycin Injection is 0.2 ml per kilogram of body weight;
- The dosage of Dexamethasone Injection is 0.2 mg per kilogram of body weight;
- The dosage of Ribavirin Injection is 0.2 ml per kilogram of body weight.
For dogs with severe coughing, Ambroxol Injection can be used, at a dosage of 0.2 ml per kilogram of body weight.
If the dog exhibits severe dyspnea, Aminophylline Injection can be used, at a dosage of 0.2 ml per kilogram of body weight, to relieve cough and wheezing symptoms.
If the dog has a severe fever, Antondine Injection can be used, at a dosage of 0.2 ml per kilogram of body weight, and the medication should be discontinued immediately after the fever subsides.
For dogs with thick nasal discharge and purulent eye discharge, Houttuynia Cordata Injection can be used, at a dosage of 0.2 ml per kilogram of body weight.

Hyperimmune Serum and Monoclonal Antibody Treatment for Canine Distemper
Medication Instructions
Since canine distemper is caused by a virus, corresponding treatment measures will be adopted.
- The dosage of Hyperimmune Serum is 0.5 to 1 ml per kilogram;
- The dosage of Monoclonal Antibodies for Canine Distemper is also 0.5 to 1 ml per kilogram.
If conditions permit, Interferon can be used, at a dosage of 0.5 to 1 ml per kilogram. Both subcutaneous and intramuscular injections are feasible. If intravenous infusion can be administered to the dog, it will be the best continuous medication plan. It is recommended to continue for 7 to 15 days until the dog’s diet, excretion, and mental state return to normal levels.
Final Reminder
If it is not possible to save the dog, there is nothing that can be done. Humans have their destiny, and dogs have theirs. Do your best and leave the rest to fate. The above medication plan only represents personal medication habits and is for reference only. It is recommended that you seek the help of a veterinarian.
Original article by KPTer, if reproduced, please cite the source: https://www.kaipet.com/en/treat-canine-distemper-comprehensive-analysis-symptoms-diagnosis-treatment-plans

Comments(2)
This is such a comprehensive guide! I’m curious, what’s the recommended vaccination schedule for puppies to best prevent distemper?
@CriticX:Thank you for your kind words! We’re glad you found the guide helpful. Regarding vaccination schedules for distemper prevention, this article focuses on treatment. For tailored advice, please consult your veterinarian or explore our site for more resources on puppy health and vaccinations.